Therapeutic apheresis procedures can be classified as either the exchange of blood components or the selective removal of specific cells.  A portion of the blood is removed or treated, with the remaining components being returned to the patient.  For guidelines on the use of Therapeutic Apheresis in Clinical Practice, please click here.

Advantages of INBC Therapeutic Apheresis

  • The apheresis service can be provided to inpatients and outpatients in the local hospital setting
  • Highly competent and experienced RN apheresis staff
  • Consultation with the INBC Medical Director available at all times
  • Consistent and current standard operating procedures
  • Quality Assurance and customer service
  • Well maintained, calibrated equipment
  • Service available 7 days/week; 24 hours /day

Physician’s Office/Hospital Responsibility for Hemapheresis Procedures

  • Identify candidates for therapeutic apheresis procedure
  • Consult with INBC Medical Director as appropriate
  • Order appropriate procedures and frequency, supervise procedure
  • Arrange for placement of apheresis/dialysis catheter as appropriate. Recommended catheters for vascular access (internal jugular placement is preferred):- permanent: Double lumen hemodialysis/hemapheresis catheter (13.5 Fr)
    – temporary: Double lumen catheter (11.5 Fr)
  • Contact INBC Clinical Services Office (509-991-3015 or 800-423-0151 X4127) to schedule procedure
  • Fax completed Hemapheresis Orders, Therapeutic Apheresis Informed Consent, patient’s current history and physical examination, laboratory data, current medication list, height, and weight to the Clinical Services Office (509-232-4523)
  • Human Progenitor Cell Collection (Stem Cell) Procedures require screening for hemoglobinopathies and a current pregnancy test for women under the age of 55 years old

Inland Northwest Blood Center Responsibility

  • Reviews orders for completeness
  • Performs procedure(s)
  • Notifies ordering physician prior to each procedure start
  • Has Medical Director review apheresis records
  • Provides educational opportunities for you and your clinical staff

Procedures Performed

Therapeutic plasma exchange (plasmapheresis) includes

  • TPE-Therapeutic Plasma exchange using fresh frozen plasma  or 5% albumin as the replacement fluid
    • Disease processes may include: Thrombotic Thrombocytopenic  Purpura (TTP), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Solid Organ Transplantation, Hypertriglyceridemia, Wegener’s Granulomatosis, Hemolytic Uremic Syndrome (HUS), Guillain-Barre, Catastrophic Antiphospholipid Syndrome (CAPS)


  • To request the related paperwork and/or forms, please contact INBC Clinical Services


  • Cytapheresis is the removal or exchange of cellular components
    • Leukocytapheresis – White blood cell depletion
      • This procedure removes an excess amount of white blood cells as seen in leukemia
    • Thrombocytapheresis – Platelet depletion
      • This is a process for the removal of large quantities of platelets (Thrombocytosis)
    • Erythrocytapheresis/ Red Blood Cell Exchange.
      • Red blood cells are removed or replaced with donor red blood cells.
        • Disease processes may include: Sickle Cell Anemia Disease, Malaria, Babesiosis, Hereditary Hemochromatosis


  • To request the related paperwork and/or forms, please contact INBC Clinical Services

Extracorporeal Photopheresis

A process of collecting, treating and reinfusing white blood cells to a patient.  The treated white cells will alter their immune response. Extracorporeal Photopheresis is used in the treatment of Cutaneous T-Cell Lymphoma, Graft Versus Host Disease (GVHD), lung and cardiac allograft rejection.


  • To request the related paperwork and/or forms, please contact INBC Clinical Services

Cellular Therapy

HPC – Hematopoietic Progenitor Stem Cells is a hematopoietic precursor cell capable of self-renewal. It can be used to achieve bone marrow reconstitution. After stimulating the bone marrow to produce stem cells, those cells are then mobilized to the circulation to be collected peripherally. The stem cells are cryo-preserved here at the Inland Northwest Blood Center to be re-infused at a later date.

  • Disease processes may include: multiple myeloma, lymphoma, neuroblastoma or other cancers.


  • To request the related paperwork and/or forms, please contact INBC Clinical Services

Dendreon Collections

  • Provenge (Sipuleucel-T) is an autologous cellular immunotherapy used for the treatment of prostate cancer
    • Autologous mononuclear cells (MNCs) are collected peripherally through a process called apheresis
    • Cell collection is performed onsite at the Inland Northwest Blood Center
    • The collected cells are shipped to an FDA approved manufacturing facility
    • The manufactured/treated cells are shipped to an infusion center (the prescribing physician’s office) where the cells are reinfused

To request the related paperwork and/or forms, please contact INBC Clinical Services

For more information, contact Inland Northwest Blood Center Clinical Services Office at:

(800) 423-0151 ext. 4127

(509) 991-3015

Fax: (509) 232-4523

Services are available 24 hours a day, 7 days a week